Panther Claw is a villainous group of beings founded and lead by Sister Jill. Unlike previous series where the members are mutants, Panther Claw in Re: Cutie Honey is composed of beings made from nano-technology, the same ones utilized by the I-System of their enemy Honey Kisaragi.
Panther Claw was founded by Sister Jill after she was reactivated by a scientist of malicious intent. Using the research of the I-System, members of Panther Claw were created including the Butler made in the image of Dr. Kisaragi after Black Claw killed him. Several years later, Panther Claw would amass their forces to attack Japan to recover the I-System and establish dominion.